8 Best AI Email Marketing for Nonprofit Organization 2025

November 3, 2025
5 min read
Tazmeen

By Tazmeen

 8 Best AI Email Marketing for Nonprofit Organization 2025

AI-powered email marketing is transforming how organizations connect with their audiences. Using advanced algorithms and data insights, these platforms analyze donor behavior, predict engagement trends, and personalize messages that truly resonate. The result is more targeted, efficient, and impactful communication that boosts engagement while saving time.

Unlike traditional email tools that only send messages, AI platforms continuously learn and improve with every campaign. They optimize timing, refine content, and personalize outreach at scale, helping organizations turn supporters into loyal donors and volunteers.

1. Mailmodo

Mailmodo is an AI-powered email marketing software that helps you create, automate, and optimize campaigns effortlessly. From planning strategy to writing copy and building journeys, Its unique interactive emails allow recipients to complete donation forms, take surveys, and engage with content without leaving their inbox.

Key Features

  • An AI assistant that generates complete email copy and campaign flows from text prompts.

  • Interactive AMP emails enabling in-email donations, forms, and polls

  • AI-powered subject line optimization based on historical performance data

  • Automated behavioral segmentation that adapts to donor engagement patterns

Pricing: It has a forever-free plan with limited features; paid plans start from $39/month.

Best For: Nonprofits seeking innovative, interactive email experiences with AI-driven content creation and high engagement rates

2. Encharge

Encharge is an AI-powered automation platform built for behaviour-based email marketing. It monitors donor actions across your website and systems, automatically triggering personalized email sequences based on specific behaviours like donations, form submissions, or page visits. The platform's AI journey builder suggests optimal campaign paths and predicts the best send times for maximum engagement.

Key Features

  • Behavior-triggered automation that responds to donor actions in real-time

  • AI-powered journey builder with smart path suggestions

  • Predictive send time optimization for improved open rates

  • Deep integrations with Stripe, CRMs, and donation platforms

Pricing: Growth Plan starts at $79/month for up to 2,000 subscribers; Premium Plan at $129/month includes Salesforce integration

Best For: Growing nonprofits needing sophisticated donor journey automation with behavior-based personalization and CRM integration

3. Rasa.io

Rasa.io revolutionizes newsletter marketing with AI-powered content curation and personalization. Rather than sending identical newsletters to everyone, Rasa.io's Smart Newsletters feature uses artificial intelligence to customize each email based on individual recipient interests and past engagement. The system automatically learns over time, continuously improving content relevance without manual intervention.

Key Features

  • AI curates unique newsletter content for each subscriber based on their interests

  • Machine learning algorithms that adapt to engagement patterns automatically

  • Multi-step email campaigns that respond to recipient interactions

  • Automated content selection from your sources and third-party feeds

Pricing: Free plan for up to 2,500 subscribers; paid plans with enhanced features available (requires demo for pricing)

Best For: Associations and nonprofits with content-heavy newsletters who want personalized engagement without manual curation work

4. Omnisend

Omnisend brings e-commerce-grade AI capabilities to email marketing with powerful automation and personalization features. The platform's AI generates subject lines, email copy, and preheaders while learning your brand's tone from past campaigns. Its AI-powered product recommender analyzes browsing behavior to suggest relevant content, and the segment builder understands plain language requests.

Key Features

  • An AI copywriter that drafts complete emails in your brand voice

  • Subject line and preheader generator optimized for engagement

  • AI-powered product/content recommendations based on behaviour

  • Natural language segment builder that creates audiences from plain text

Pricing: Free plan for up to 250 contacts; Standard from $16/month; Pro from $59/month

Best For: Nonprofits running merchandise stores or needing ecommerce-style personalization with sophisticated AI-driven automation

5. HubSpot AI

HubSpot AI integrates comprehensive marketing automation with an AI-powered CRM designed for relationship management. The platform segments donors based on behavior patterns, predicts giving trends using machine learning, and personalizes outreach across email, social media, and web. Qualified nonprofits receive a substantial 40% discount on Marketing Hub plans.

Key Features

  • AI-powered CRM that segments donors by behavior and predicts trends

  • Automated workflow builder with AI suggestions for optimization

  • Machine learning for predictive lead scoring and content recommendations

  • Integrated analytics tracking donor journey from first touch to conversion

Pricing: Free CRM available; Marketing Hub Starter at $15/month (40% nonprofit discount available); Professional at $890/month

Best For: Established nonprofits needing an all-in-one CRM and marketing automation platform with enterprise-level AI capabilities

6. Seventh Sense

Seventh Sense specializes in AI-driven send time optimization for HubSpot and Marketo users. The platform analyzes each contact's historical email engagement patterns, building individual profiles to determine precisely when each person is most likely to open and interact with emails. It spreads delivery across customizable windows from one hour to seven days.

Key Features

  • Machine learning algorithms predict optimal send times for each contact

  • Automated email throttling to improve deliverability and sender reputation

  • Dynamic frequency optimization based on individual engagement preferences

  • Engagement-based segmentation showing active, occasional, and at-risk contacts

Pricing: Pricing scales based on contact volume; contact for a custom quote

Best For: Nonprofits using HubSpot or Marketo who want to maximize email engagement through AI-powered delivery optimization

7. ActiveCampaign

ActiveCampaign combines advanced marketing automation with AI features, including predictive sending, content recommendations, and machine learning-powered segmentation. The platform's AI analyzes campaign performance to suggest optimal send times, predicts which leads are most likely to convert, and automatically segments audiences for targeted messaging.

Key Features

  • Predictive sending AI determines the best times for individual recipients

  • Machine learning for lead scoring and conversion prediction

  • AI-powered content recommendations based on subscriber behavior

  • Automated split testing with AI optimization for best-performing variants

Pricing: Plans start at $15/month; 20% nonprofit discount available

Best For: Nonprofits requiring sophisticated multi-step automation with AI-enhanced personalization and predictive analytics for donor engagement

8. Brevo (formerly Sendinblue)

Brevo delivers AI-enhanced multi-channel marketing across email, SMS, and WhatsApp from a single platform. The platform uses AI for predictive sending, subject line suggestions, and automated segmentation. Its unique pricing model charges based on emails sent rather than subscriber count, making it cost-effective for nonprofits with large but infrequently contacted lists.

Key Features

  • AI predictive sending optimizes delivery times for maximum engagement

  • Machine learning-powered segmentation based on behavior and attributes

  • Multi-channel automation coordinating email, SMS, and chat communications

  • Built-in CRM with AI insights for donor relationship management

Pricing: Free plan includes unlimited contacts; Starter from $8.08/month; Business from $16.17/month (15% nonprofit discount)

Best For: Nonprofits needing multi-channel communication with AI optimization and unlimited contact storage at affordable pricing

Final Thoughts

Selecting the right AI-powered email marketing platform represents a strategic investment in your nonprofit's communication infrastructure and donor relationships. The optimal choice depends on your organization's size, technical capabilities, budget constraints, and specific goalswhether fundraising, volunteer recruitment, or supporter engagement, but the one that aligns with your mission and grows alongside your organization. 

Take advantage of free trials and nonprofit discounts to test platforms firsthand. Focus on reducing friction in donor journeys, automating repetitive tasks, and personalizing communications at scale, allowing your team to concentrate on advancing your mission rather than managing email campaigns.