9 Best AI Email Marketing Software for CRM 2025

November 6, 2025
5 min read
Tazmeen

By Tazmeen

 9 Best AI Email Marketing Software for CRM 2025

Today's businesses need more than traditional email tools; they require AI email marketing software for CRM integration that can predict customer behavior, personalize content at scale, and automate complex workflows seamlessly. Finding the best AI email marketing software for CRM integration in 2025 means looking for platforms that combine intelligent automation with robust customer data management.

These AI-powered solutions enable marketers to send the right message to the right person at precisely the right time, all while maintaining deep integration with existing CRM systems. 

Top 9 email marketing software for CRM

Here are the top 9 AI email marketing tools specifically designed for CRM that could help you deliver results.

1. Mailmodo

Mailmodo is an AI-powered email marketing software that helps you create, automate, and optimize campaigns effortlessly. From planning strategy to writing copy and building journeys, Mailmodo’s AI Agents handle it all, with no technical expertise needed. It’s the fastest way to send smart, interactive, and high-performing emails.

With seamless CRM integrations via Zapier, HubSpot, Salesforce, and more, Mailmodo transforms how businesses engage their audiences. The AI-powered email builder helps create dynamic campaigns that significantly boost engagement rates by allowing recipients to complete actions such as form submissions, surveys, and bookings without leaving their inboxes.

Key Features

  • AI Email Assistant: Start your email marketing journey with AI. Get campaign strategies, subject lines, and contextual copy suggestions by simply chatting with Mailmodo’s AI Agents. Plan your emails, journeys, and goals with no manual effort required.

  • In-Email Transaction Capabilities: Enable customers to browse product catalogs, add items to cart, and complete checkout flows directly within emails using deep linking technology that reduces purchase friction by up to 280%

  • AI-Powered Email Builder: Design polished, on-brand emails in seconds. Generate complete email layouts or remix existing ones, change fonts, colors, or content instantly using AI commands.

  • AI Audience Segmentation Made Simple: Target the right people effortlessly. Just describe your audience, and Mailmodo’s AI will create accurate segments based on your data, ready for personalization.

Pricing

  • Free: It has a forever-free plan with limited features

  • Lite: $39/month - 20,000 email credits, 1 team member

  • Pro: $79/month - 25,000 email credits, 3 team members

  • Max: $159/month - 37,500 email credits, 5 team members

Best For

Marketers, eCommerce brands, and SaaS businesses are seeking interactive, high-performing email experiences with strong CRM integration and AI-powered automation.

2.​‍​‌‍​‍‌​‍​‌‍​‍‌ HubSpot 

HubSpot's AI email marketing software for CRM integration provides a seamless automating platform for marketing directly built into the powerful CRM system. The platform, with the help of AI, adjusts email send times, uses customer data to personalize content, and even figures out which leads will most probably convert.

HubSpot's AI-powered capabilities entail smart segmentation, behavior-triggered emails, and predictive lead scoring that enable marketing teams to be more productive. The smooth union of email marketing with CRM data makes sure that every communication is backed up by extensive customer insights.

Key Features

  • Breeze Intelligence Buyer Intent Tracking: Interprets the behavior of anonymous visitors to a website across different touchpoints to recognize high-intent prospects before they convert, thereby scoring leads on the depth of engagement and purchase signals

  • AI Content Remix for Multi-Channel: Without any manual intervention, it changes a single video or blog post to a full-fledged campaign with social clips, email copy, audio content, and ad variations, thereby immensely cutting the content creation time

  • Breeze Copilot Contextual Assistant: Cooperates with you like an AI teammate who gets your full business scenario from CRM data, helping you with meeting briefs, generating strategic analysis, and drafting responses based on the company-specific information

  • AI-powered Workflow Builder from Plain Language: Helps in the creation of very complex automation sequences just by giving the result description in natural language.

Pricing

  • Free: Up to 2,000 emails/month, 1,000 contacts, basic automation

  • Starter: $20/month per seat - 1,000 contacts included

  • Professional: $890/month - Advanced automation, 3 seats, requires annual commitment

  • Enterprise: Custom pricing - Full omnichannel marketing capabilities

Best For

B2B companies, businesses with long sales cycles, and teams needing comprehensive marketing automation with native CRM integration and inbound marketing strategies.

3. ActiveCampaign

ActiveCampaign is a leading AI-powered email marketing software for CRM that features advanced automation workflows and predictive intelligence. The platform's main strength lies in its AI-powered automation builder that can create intricate customer journeys and adjust the sequences based on the behavior of the recipients.

ActiveCampaign, with its built-in CRM capabilities and AI-optimized email delivery, which is able to predict the best send times, lets businesses carry out the personalization of their campaigns on a large scale. 

Key Features

  • Predictive Content Multi-Variant Matching: Generates up to 5 different versions of an email and uses machine learning across 300 unique content dimensions to automatically identify for each recipient their preferred tone, length, and style

  • Win Probability Scoring with Transparency: Employs machine learning to find the percentage chance of closing each deal and, at the same time, unveils exactly what actions are responsible for the predictions.

  • Sentiment Analysis Tracking: Keeps an eye on customer feelings and views in all their interactions by using thousands of data points and real-time behavioral signals.

  • Conditional Content Layering: Facilitates manual audience division within campaigns coupled with AI predictions, thus producing extremely personalized messages where different people get completely different versions of an email based on CRM attributes and behavior

Pricing

  • Starter: $15/month - Basic email marketing with limited automation

  • Plus: $49/month - Unlimited automation, CRM, A/B testing, landing pages

  • Pro: $79/month - AI-driven automation, predictive sending, advanced segmentation

  • Enterprise: $145/month - Custom CRM features, premium segmentation, dedicated support

Best For

E-commerce brands, service-based businesses, and companies need complex customer journeys with AI-powered recommendations and robust CRM ​‍​‌‍​‍‌​‍​‌‍​‍‌integration.

4. Brevo​‍​‌‍​‍‌​‍​‌‍​‍‌ (formerly Sendinblue)

Brevo has a wide range of intelligent features AI email marketing software for CRM integration, which includes send-time optimization and personalized content recommendations. Efficiently and cost-effectively, the platform integrates the combination of email and SMS marketing with CRM capabilities.

Being an all-in-one tool, Brevo enables AI email marketing software for CRM at the level of small businesses still to be there without holding back on the feature level of advanced ones.

Key Features

  • Individual Subscriber Send-Time Prediction: looks over the past email opening events of each contact over the days and hours to find and immediately plan the delivery when they are personally most likely to engage.

  • Real-Time Deliverability: API Scanning is a never-ending activity that tracks the sender's reputation, does the email verification right away, and changes the sending style automatically to stay away from spam filters and get inbox placement

  • Unified Conversation Inbox: Gathers all the conversations with the customers through email, SMS, chat, and social media into one CRM platform.

  • Machine Learning Content Suggestions: by running the past campaign data and finding the conversion drivers for each different audience-derived segment.

Pricing

  • Free: 300 emails per day, basic features, unlimited contacts

  • Starter: $9/month - 5,000 emails per month, no daily limit

  • Business: $18/month - Marketing automation, A/B testing, predictive sending, phone support

  • Enterprise: Custom Pricing - Full Features, Dedicated Support, Infinite Contacts

Best For

Small to mid-sized businesses seeking affordably-priced, unified communication systems with AI capabilities, and startups requiring CRM and marketing on one platform.

5. Ortto

Ortto delivers high-level AI email marketing software for seamless CRM integration, tailored to data-driven teams that demand advanced personalization and analytics on a large scale. The platform merges the customer data platform (CDP) features with marketing automation, employing AI to recommend the best campaign strategies and to forecast customer behavior.

Marketers can use Ortto's visual journey builder to design complex, multi-channel workflows, while AI-driven segmentation guarantees that the right people get the message. Ortto aids businesses in recognizing customer lifecycles and making the most out of their marketing budget, thus being an excellent AI email marketing software for CRM-centric organizations.

Key Features

  • AI Campaign Performance Forecasting: Using data patterns, audience characteristics, and content variables, it foresees campaign results even before the launch, thus suggesting the most efficient use of the budget that yields the highest ROI and minimizes the waste of resources

  • Customer Data Platform Unification: No manual work required; the system automatically combines customer data from different sources into one profile, settles identity issues, and updates records with behavioral, demographic, and transactional data in real-time

  • Dynamic Journey Path Recommendations: Determines the subsequent best actions and other workflow branches to be used based on machine learning study of the similar customer segments, thus perpetually tweaking automation routes for higher conversion

Pricing

  • Professional: $509/month - Core marketing automation with AI insights and an annual billing cycle

  • Business: $849/month - Priority support, transactional messaging, and advanced reporting

  • Enterprise: $1,699/month - Dedicated consultants, SLAs, custom setups, and multiple workspaces

Best For

Ambitious teams and big companies are looking for in-depth personalization, analytics, AI-driven campaign optimization, along full CRM data ​‍​‌‍​‍‌​‍​‌‍​‍‌management.

6.​‍​‌‍​‍‌​‍​‌‍​‍‌ Customer.io

Customer.io is the best behavior-driven AI email marketing software for CRM integration. The company is known for delivering real-time, that is, triggered messages based on a user's actions in a product or a website. So as to segment audiences on the fly and use the maximum personalization of the communication with unlimited profile attributes and event data, the platform deploys AI.

The sophisticated automation of Customer.io is a complex multi-step workflow that starts immediately after a customer behavior, the start of the chain in the SaaS companies and product-led businesses is perfect. Although the AI-driven scheme can execute billions of API calls and at the same time keep the enterprise-grade scalability.

Key Features

  • Real-Time Event Stream Processing: The process is very fast, and personalized messages are initiated straight away as users perform certain actions, leave features, or hit usage milestones

  • Liquid Template Dynamic Content: With the help of this advanced templating language, developers can create limitless customisable email content that not only fetches live data from APIs but also does calculations and renders different layouts depending on attributes of the individual user

  • Broadcast Holdout Testing: The control group is automatically held back from receiving campaigns to gauge the true increment of the lift, and ROI AI is used to decide the holdout percentages that are the most statistically significant

  • Data Warehouse Native Integrations: It supports Snowflake, BigQuery, and Redshift connections so that customer data can be locally synced, thus enabling advanced segmentation on any data point without the need for complex ETL processes

Pricing

  • Essentials: 5,000 profiles, 1 million messages, basic features - $100 per month

  • Premium: From $1,000 per month - Custom profiles/emails, premium support, 90-day onboarding, data warehouse integrations

  • Enterprise: Advanced features, HIPAA compliance, dedicated support - Custom pricing

Best For

Real-time, behavior-driven engagement with deep product integration is a must for SaaS platforms, product-led companies, and subscription-based businesses.

7. Klaviyo

Klaviyo is an AI-powered email marketing tool that integrates with CRM to provide customer-centric, data-driven growth specifically for e-commerce businesses. The platform's strength lies in its sophisticated segmentation and targeting capabilities.

The machine learning models of Klaviyo predict customer lifetime value, identify which customers are at risk, and determine the best product suggestions for every individual. Klaviyo solves the online retail challenges with AI marketing solutions for CRM that are the perfect fit for e-commerce through predictive analytics and automated workflows.

Key Features

  • Predictive Customer Lifetime Value (CLV): Routinely CLV model routinely calculates expected total revenue during the customer lifecycle.

  • Churn Risk Identification: Utilizes machine learning to determine customers exhibiting early signs of disengagement and automatically prompts the reactivation email campaign options.

  • Smart Product Recommendation Engine: The system evaluates browsing history, previously bought products, and behaviour of similar customers so as to be able to dynamically add personalized product suggestions that take 30% more customer clicks than general recommendations.

  • Flow Performance Benchmarking: Your automation metrics will be compared with the average and performance of the best players in your category, and AI suggestions will be given for closing performance gaps

Pricing

  • Free: 500 emails/month, 150 SMS credits, basic analytics

  • Email: Beginning at $45 per month - 15,000 emails/month, advanced analytics, segmentation

  • Email + SMS: Pricing based on features - Combined multi-channel messaging with full features

Best For

Online retailers, e-commerce brands, and Shopify store owners require elaborate segmentation, accurate analytics, and automated campaigns that drive ​‍​‌‍​‍‌​‍​‌‍​‍‌revenue.

8.​‍​‌‍​‍‌​‍​‌‍​‍‌ Instantly.ai

Instantly.ai is primarily an AI email marketing tool aimed at CRM integration and focused on cold email outreach and lead generation on a large scale. To attract the attention of customers, the platform employs artificial intelligence to create personalized communication campaigns, to deliver them in an optimized manner, and to make the prospecting process free of manual intervention.

The platform's AI extracts the response patterns, indicates the best time for the dispatch, and keeps improving the success rate of the campaigns, that it a must-have AI email marketing software for CRM-driven sales organizations targeting customer acquisition.

Key Features

  • Unlimited Email Account Rotation: Connects and manages hundreds of sending accounts simultaneously, automatically rotating sends across domains to maximize volume while maintaining individual sender reputation and avoiding ESP limits

  • AI-Powered Email Warm-Up: Automatically exchanges emails with a network of real accounts to build sender credibility, gradually increasing volume while monitoring deliverability metrics to ensure inbox placement before launching campaigns.

  • Spam Filter Avoidance Intelligence: Implements machine learning to scrutinize the email for certain trigger words, wrongly formatted parts, and other related issues that might lead to the email being labeled as spam, and at the same time, it offers the solution, allowing the sender to get much better deliverability results in real-time

  • Built-In Lead Database Access: Offers the direct connection to over a hundred million verified business contacts with AI-powered filters that will produce B2B leads that are hottest based on the company's utilization of the technology, recent funding, hiring, and changes

Pricing

  • Growth: $30/month - 1,000 active leads, unlimited email accounts, basic features

  • Hypergrowth: $77.6/month - 5,000 active leads, advanced features, and priority support

  • Enterprise: Custom pricing - No limits on the leads, a dedicated account manager, and white-label options

Best For

B2B companies, agencies, freelancers, and sales teams that rely on cold emailing to generate leads and scale their prospecting efforts.

9. ClickDimensions

ClickDimensions acts as AI email marketing software tailored for CRM integration and built strictly for Microsoft Dynamics users. The platform integrates smoothly with Dynamics 365 and employs AI to enhance campaign performance with techniques like smart lead scoring and behavioral tracking.

ClickDimensions offers AI email marketing software natively integrated with CRM, which means no more data loss and quicker marketing operations right in the familiar Dynamics environment.

Key Features

  • Native Microsoft Dynamics Integration: The software performs a complete cycle within the Dynamics 365 interface with smooth CRM data synchronization, thus doing away with third-party connectors or the need for exports between the marketing and sales systems

  • AI-Powered Lead Scoring: Uses machine learning to assign the highest priority to those prospects who show the most engagement and, at the same time, meet the demographic and behavioral criteria. In addition, the scoring models are updated as more data is collected

  • Behavioral Tracking and Analytics: Tracks customers' behaviors through email, web visits, form submissions, and content downloads to not only personalize the next steps but also to notify the sales team about the customers showing the highest level of interest

  • Predictive Campaign Optimization: The AI in question draws on the past to recommend changes and lets the user know when they can get the best results by sending the email, using the subject line intended, and choosing the content format that the segment of the audience will appreciate

Pricing

  • Standard: Starting at $600/month - Basic email marketing features with AI capabilities

  • Professional: Starting at $1,200/month - Sophisticated automation, lead scoring, analytics

  • Enterprise: Custom pricing - Full range of features, dedicated support, unlimited users

Best For

Microsoft Dynamics 365 users, large-scale organizations operating within the Microsoft ecosystem, and companies in need of native CRM integration with AI-driven marketing ​‍​‌‍​‍‌​‍​‌‍​‍‌capabilities.

Final Thoughts

Selecting the right AI email marketing software for CRM integration can fundamentally transform how your business connects with customers and drives revenue growth. The platforms featured in this guide represent the leading edge of AI-powered marketing technology, each offering unique strengths in automation, personalization, and CRM connectivity. 

When evaluating AI email marketing software for CRM, consider factors beyond just features and pricing, think about scalability, ease of implementation, integration capabilities with your existing tech stack, and the level of AI sophistication that matches your team's expertise.